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Gastrointestinal Carriage Is a Major Reservoir of Klebsiella pneumoniae Infection in Intensive Care Patients
Author(s) -
Claire L. Gorrie,
Mirjana Mirčeta,
Ryan R. Wick,
David Edwards,
Nicholas R. Thomson,
Richard A. Strugnell,
Nigel F. Pratt,
Jill S. Garlick,
Kerri M. Watson,
David Pilcher,
Steve McGloughlin,
Denis W. Spelman,
Adam Jenney,
Kathryn E. Holt
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix270
Subject(s) - carriage , klebsiella pneumoniae , medicine , intensive care unit , colonization , odds ratio , epidemiology , microbiology and biotechnology , biology , escherichia coli , pathology , biochemistry , gene
Klebsiella pneumoniae is an opportunistic pathogen and leading cause of hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk. Klebsiella pneumoniae is part of the healthy human microbiome, providing a potential reservoir for infection. However, the frequency of gut colonization and its contribution to infections are not well characterized.

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