Increased Endovascular Staphylococcus aureus Inoculum Is the Link Between Elevated Serum Interleukin 10 Concentrations and Mortality in Patients With Bacteremia | Zendy

Warren E. Rose | Zendy; Sanjay K. Shukla | Zendy; Andrew D. Berti | Zendy; Mary S. Hayney | Zendy; Kelsey M. Henriquez | Zendy; Andrea Ranzoni | Zendy; Matthew A. Cooper | Zendy; Richard A. Proctor | Zendy; Victor Nizet | Zendy; George Sakoulas | Zendy

Open Access

Increased Endovascular Staphylococcus aureus Inoculum Is the Link Between Elevated Serum Interleukin 10 Concentrations and Mortality in Patients With Bacteremia

Author(s) -

Warren E. Rose,

Sanjay K. Shukla,

Andrew D. Berti,

Mary S. Hayney,

Kelsey M. Henriquez,

Andrea Ranzoni,

Matthew A. Cooper,

Richard A. Proctor,

Victor Nizet,

George Sakoulas

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix157

Subject(s) - medicine , bacteremia , staphylococcus aureus , micrococcaceae , staphylococcal infections , microbiology and biotechnology , bacteria , antibiotics , genetics , biology

Cell wall peptidoglycan stimulates interleukin 10 (IL-10) production in Staphylococcus aureus bacteremia (SaB) animal models, but clinical data are not available. This study evaluates the impact of intravascular bacterial cell numbers (ie, the level of bacteremia), in patients at the time of clinical presentation on IL-10 production and its association with S. aureus bacteremia (SaB) mortality.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research