Evaluation of Pneumococcal Load in Blood by Polymerase Chain Reaction for the Diagnosis of Pneumococcal Pneumonia in Young Children in the PERCH Study
Author(s) -
Maria Deloria Knoll,
Susan C. Morpeth,
J. Anthony G. Scott,
Nora L. Watson,
Daniel E. Park,
Henry C. Baggett,
W. Abdullah Brooks,
Daniel R. Feikin,
Laura L. Hammitt,
Stephen R. C. Howie,
Karen L. Kotloff,
Orin S. Levine,
Katherine L. O’Brien,
Donald M. Thea,
Dilruba Ahmed,
Martín Antonio,
Juliet O. Awori,
Vicky L. Baillie,
James Chipeta,
Andrea N. DeLuca,
Michel Dione,
Amanda J. Driscoll,
Melissa M. Higdon,
Anchalee Jatapai,
Ruth A. Karron,
Razib Mazumder,
David P. Moore,
James Mwansa,
Sammy Nyongesa,
Christine Prosperi,
Phil Seidenberg,
Duangkamon Siludjai,
Samba O. Sow,
Boubou Tamboura,
Scott L. Zeger,
David R. Murdoch,
Shabir A. Madhi,
Nicholas Fancourt,
Wei Fu,
E. Wangeci Kagucia,
Mengying Li,
Zhenke Wu,
Jane Crawley,
Hubert P. Endtz,
Khalequ Zaman,
Doli Goswami,
Lokman Hossain,
Yasmin Jahan,
Hasan Ashraf,
Bernard E. Ebruke,
Jessica McLellan,
Eunice Machuka,
Arifin Shamsul,
Syed M. A. Zaman,
Grant Mackenzie,
Alice Kamau,
Sidi Kazungu,
Micah Silaba Ominde,
Milagritos D. Tapia,
Mamadou Sylla,
Uma Onwuchekwa,
Nana Kourouma,
Aliou Touré,
Peter V. Adrian,
Locadiah Kuwanda,
Azwifarwi Mudau,
Michelle J. Groome,
Nasreen Mahomed,
Somsak Thamthitiwat,
Susan A. Maloney,
Charatdao Bunthi,
Julia Rhodes,
Pongpun Sawatwong,
Pasakorn Akarasewi,
Lawrence Mwananyanda,
Somwe Wa Somwe,
Geoffrey Kwenda,
Trevor P. Anderson,
Joanne Mitchell
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix149
Subject(s) - medicine , pneumonia , pneumococcal pneumonia , venous blood , streptococcus pneumoniae , community acquired pneumonia , gastroenterology , chest radiograph , immunology , lung , microbiology and biotechnology , biology , antibiotics
Detection of pneumococcus by lytA polymerase chain reaction (PCR) in blood had poor diagnostic accuracy for diagnosing pneumococcal pneumonia in children in 9 African and Asian sites. We assessed the value of blood lytA quantification in diagnosing pneumococcal pneumonia.
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