Is Higher Viral Load in the Upper Respiratory Tract Associated With Severe Pneumonia? Findings From the PERCH Study | Zendy

Daniel R. Feikin | Zendy; Wei Fu | Zendy; Daniel E. Park | Zendy; Qiyuan Shi | Zendy; Melissa M. Higdon | Zendy; Henry C. Baggett | Zendy; W. Abdullah Brooks | Zendy; Maria Deloria Knoll | Zendy; Laura L. Hammitt | Zendy; Stephen R. C. Howie | Zendy; Karen L. Kotloff | Zendy; Orin S. Levine | Zendy; Shabir A. Madhi | Zendy; J. Anthony G. Scott | Zendy; Donald M. Thea | Zendy; Peter V. Adrian | Zendy; Martín Antonio | Zendy; Juliet O. Awori | Zendy; Vicky L. Baillie | Zendy; Andrea N. DeLuca | Zendy; Amanda J. Driscoll | Zendy; Bernard E. Ebruke | Zendy; Doli Goswami | Zendy; Ruth A. Karron | Zendy; Mengying Li | Zendy; Susan C. Morpeth | Zendy; John Mwaba | Zendy; James Mwansa | Zendy; Christine Prosperi | Zendy; Pongpun Sawatwong | Zendy; Samba O. Sow | Zendy; Milagritos D. Tapia | Zendy; Toni Whistler | Zendy; Khalequ Zaman | Zendy; Scott L. Zeger | Zendy; Katherine L. O’Brien | Zendy; David R. Murdoch | Zendy; Nicholas Fancourt | Zendy; E. Wangeci Kagucia | Zendy; Zhenke Wu | Zendy; Nora L. Watson | Zendy; Jane Crawley | Zendy; Hubert P. Endtz | Zendy; Lokman Hossain | Zendy; Yasmin Jahan | Zendy; Hasan Ashraf | Zendy; Jessica McLellan | Zendy; Eunice Machuka | Zendy; Arifin Shamsul | Zendy; Syed M. A. Zaman | Zendy; Grant Mackenzie | Zendy; Alice Kamau | Zendy; Sidi Kazungu | Zendy; Micah Silaba Ominde | Zendy; Mamadou Sylla | Zendy; Boubou Tamboura | Zendy; Uma Onwuchekwa | Zendy; Nana Kourouma | Zendy; Aliou Touré | Zendy; David P. Moore | Zendy; Locadiah Kuwanda | Zendy; Azwifarwi Mudau | Zendy; Michelle J. Groome | Zendy; Nasreen Mahomed | Zendy; Somsak Thamthitiwat | Zendy; Susan A. Maloney | Zendy; Charatdao Bunthi | Zendy; Julia Rhodes | Zendy; Pasakorn Akarasewi | Zendy; Lawrence Mwananyanda | Zendy; James Chipeta | Zendy; Phil Seidenberg | Zendy; Somwe Wa Somwe | Zendy; Geoffrey Kwenda | Zendy; Trevor P. Anderson | Zendy; Joanne Mitchell | Zendy

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Is Higher Viral Load in the Upper Respiratory Tract Associated With Severe Pneumonia? Findings From the PERCH Study

Author(s) -

Daniel R. Feikin,

Wei Fu,

Daniel E. Park,

Qiyuan Shi,

Melissa M. Higdon,

Henry C. Baggett,

W. Abdullah Brooks,

Maria Deloria Knoll,

Laura L. Hammitt,

Stephen R. C. Howie,

Karen L. Kotloff,

Orin S. Levine,

Shabir A. Madhi,

J. Anthony G. Scott,

Donald M. Thea,

Peter V. Adrian,

Martín Antonio,

Juliet O. Awori,

Vicky L. Baillie,

Andrea N. DeLuca,

Amanda J. Driscoll,

Bernard E. Ebruke,

Doli Goswami,

Ruth A. Karron,

Mengying Li,

Susan C. Morpeth,

John Mwaba,

James Mwansa,

Christine Prosperi,

Pongpun Sawatwong,

Samba O. Sow,

Milagritos D. Tapia,

Toni Whistler,

Khalequ Zaman,

Scott L. Zeger,

Katherine L. O’Brien,

David R. Murdoch,

Nicholas Fancourt,

E. Wangeci Kagucia,

Zhenke Wu,

Nora L. Watson,

Jane Crawley,

Hubert P. Endtz,

Lokman Hossain,

Yasmin Jahan,

Hasan Ashraf,

Jessica McLellan,

Eunice Machuka,

Arifin Shamsul,

Syed M. A. Zaman,

Grant Mackenzie,

Alice Kamau,

Sidi Kazungu,

Micah Silaba Ominde,

Mamadou Sylla,

Boubou Tamboura,

Uma Onwuchekwa,

Nana Kourouma,

Aliou Touré,

David P. Moore,

Locadiah Kuwanda,

Azwifarwi Mudau,

Michelle J. Groome,

Nasreen Mahomed,

Somsak Thamthitiwat,

Susan A. Maloney,

Charatdao Bunthi,

Julia Rhodes,

Pasakorn Akarasewi,

Lawrence Mwananyanda,

James Chipeta,

Phil Seidenberg,

Somwe Wa Somwe,

Geoffrey Kwenda,

Trevor P. Anderson,

Joanne Mitchell

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix148

Subject(s) - viral load , viral pneumonia , pneumonia , medicine , receiver operating characteristic , respiratory tract , immunology , virology , virus , respiratory system , covid-19 , disease , infectious disease (medical specialty)

The etiologic inference of identifying a pathogen in the upper respiratory tract (URT) of children with pneumonia is unclear. To determine if viral load could provide evidence of causality of pneumonia, we compared viral load in the URT of children with World Health Organization-defined severe and very severe pneumonia and age-matched community controls.

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