Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis | Zendy

Frédéric Lamoth | Zendy; Shimin Jasmine Chung | Zendy; Lauro Damonti | Zendy; Barbara D. Alexander | Zendy

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Changing Epidemiology of Invasive Mold Infections in Patients Receiving Azole Prophylaxis

Author(s) -

Frédéric Lamoth,

Shimin Jasmine Chung,

Lauro Damonti,

Barbara D. Alexander

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix130

Subject(s) - posaconazole , voriconazole , medicine , epidemiology , azole , aspergillosis , aspergillus , retrospective cohort study , intensive care medicine , antifungal , microbiology and biotechnology , dermatology , immunology , biology

Breakthrough invasive mold infections (IMIs) that occur during posaconazole or voriconazole prophylaxis are rare complications for which epidemiological data are lacking. This retrospective analysis comparing 24 microbiologically documented breakthrough with 66 nonbreakthrough IMIs shows a shift towards non-Aspergillus molds with a significantly increased proportion of rare multidrug-resistant molds.

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