Impact of Tenofovir on Hepatitis Delta Virus Replication in the Swiss Human Immunodeficiency Virus Cohort Study
Author(s) -
Charles Béguelin,
Nicole Friolet,
Darius Moradpour,
Roland Sahli,
Franziska SuterRiniker,
Alexander U. Lüthi,
Matthias Cavassini,
Huldrych F. Günthard,
Manuel Battegay,
Enos Bernasconi,
Patrick Schmid,
Alexandra Calmy,
Andrew Atkinson,
Andri Rauch,
Gilles Wandeler
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix125
Subject(s) - virology , medicine , hepatitis delta , hepatitis d virus , virus , viral disease , hepatitis d , sida , cohort , hepatitis b virus , hepatitis c virus , hbsag
We analyzed changes in hepatitis B virus and hepatitis delta virus (HDV) viral loads (VL) during tenofovir-containing antiretroviral therapy among patients with a replicating HDV infection in the Swiss HIV Cohort Study. Only 28.6% experienced a ≥2.0 log reduction in HDV RNA, and 14.3% had undetectable HDV VL within 5 years.
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