Open AccessAngiostrongylus cantonensis Is an Important Cause of Eosinophilic Meningitis in Southern Vietnam
Author(s) -
Angela McBride,
Tran Thi Hong Chau,
Nguyen Thi Thu Hong,
Nguyen Thi Hoang,
Nguyen To Anh,
Tran Tan Thanh,
Tran Thi Hue Van,
Le Thi Thanh Xuan,
Tran Phu Manh Sieu,
Le Hong Thai,
Ly Van Chuong,
Dinh Xuan Sinh,
Nguyen Duy Phong,
Nguyen Hoan Phu,
Jeremy Day,
Ho Dang Trung Nghia,
Tran Tinh Hien,
Nguyễn Văn Vĩnh Châu,
Guy Thwaites,
Le Van Tan
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix118
Subject(s) - angiostrongylus cantonensis , medicine , eosinophilia , meningitis , eosinophilic , pathology , immunology , pediatrics , helminths
We utilized polymerase chain reaction (PCR) to demonstrate that Angiostrongylus cantonensis was responsible for 67.3% of 55 cases of eosinophilic meningitis from a cohort of 1,690 adult patients with CNS infection at a tertiary hospital in southern Vietnam. Longer duration of illness, depressed consciousness, and peripheral blood eosinophilia were associated with PCR positivity.
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