Improved Survival and Cure Rates With Concurrent Treatment for Multidrug-Resistant Tuberculosis–Human Immunodeficiency Virus Coinfection in South Africa
Author(s) -
James C. M. Brust,
Neha Shah,
Koleka Mlisana,
Pravi Moodley,
Salim Allana,
Angela Campbell,
Brent A. Johnson,
Iqbal Master,
Thuli Mthiyane,
Simlatha Lachman,
Lee-Megan Larkan,
Yuming Ning,
Amyn A. Malik,
Jonathan P. Smith,
Neel R. Gandhi
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix1125
Subject(s) - coinfection , tuberculosis , human immunodeficiency virus (hiv) , multiple drug resistance , medicine , virology , aids related opportunistic infections , antiretroviral therapy , immunology , sida , drug resistance , viral disease , viral load , biology , microbiology and biotechnology , pathology
Mortality in multidrug-resistant (MDR) tuberculosis-human immunodeficiency virus (HIV) coinfection has historically been high, but most studies predated the availability of antiretroviral therapy (ART). We prospectively compared survival and treatment outcomes in MDR tuberculosis-HIV-coinfected patients on ART to those in patients with MDR tuberculosis alone.
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