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Atypical Skeletal Muscle Profiles in Human Immunodeficiency Virus-Infected Asymptomatic Middle-Aged Adults
Author(s) -
Thanh Nga Tran,
Viola Guardigni,
Karol M. Pencina,
Anthony A. Amato,
Michael S. Floyd,
Brooke Brawley,
Brian Mozeleski,
Jennifer McKin,
Erin Woodbury,
Emily Heckel,
Zhuoying Li,
Tom Storer,
Paul E. Sax,
Monty Montano
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix1121
Subject(s) - medicine , immunosenescence , asymptomatic , biomarker , multicenter aids cohort study , population , immunology , inflammation , systemic inflammation , sarcopenia , immune system , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy , biology , biochemistry , environmental health
Human immunodeficiency virus (HIV)-infected individuals are at increased risk of age-associated functional impairment, even with effective antiretroviral therapy (ART). A concurrent characterization of skeletal muscle, physical function, and immune phenotype in aviremic middle-aged HIV-infected adults represents a knowledge gap in prognostic biomarker discovery.

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