Contribution of Maternal Antiretroviral Therapy and Breastfeeding to 24-Month Survival in Human Immunodeficiency Virus-Exposed Uninfected Children: An Individual Pooled Analysis of African and Asian Studies | Zendy

Shino Arikawa | Zendy; Nigel Rollins | Zendy; Gonzague Jourdain | Zendy; Jean H. Humphrey | Zendy; Athena P. Kourtis | Zendy; Irving Hoffman | Zendy; Max Essex | Zendy; Tim Farley | Zendy; Hoosen Coovadia | Zendy; Glenda Gray | Zendy; Louise Kuhn | Zendy; Roger Shapiro | Zendy; Valériane Leroy | Zendy; Robert C. Bollinger | Zendy; Carolyne OnyangoMakumbi | Zendy; Shahin Lockman | Zendy; Carina Marquez | Zendy; Tanya Doherty | Zendy; François Dabis | Zendy; Laurent Mandelbrot | Zendy; Sophie Le Cœur | Zendy; Matthieu Rolland | Zendy; Pierre Joly | Zendy; MarieLouise Newell | Zendy; Renaud Becquet | Zendy

Open Access

Contribution of Maternal Antiretroviral Therapy and Breastfeeding to 24-Month Survival in Human Immunodeficiency Virus-Exposed Uninfected Children: An Individual Pooled Analysis of African and Asian Studies

Author(s) -

Shino Arikawa,

Nigel Rollins,

Gonzague Jourdain,

Jean H. Humphrey,

Athena P. Kourtis,

Irving Hoffman,

Max Essex,

Tim Farley,

Hoosen Coovadia,

Glenda Gray,

Louise Kuhn,

Roger Shapiro,

Valériane Leroy,

Robert C. Bollinger,

Carolyne OnyangoMakumbi,

Shahin Lockman,

Carina Marquez,

Tanya Doherty,

François Dabis,

Laurent Mandelbrot,

Sophie Le Cœur,

Matthieu Rolland,

Pierre Joly,

MarieLouise Newell,

Renaud Becquet

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix1102

Subject(s) - breastfeeding , medicine , hazard ratio , proportional hazards model , infant mortality , population , child mortality , breast feeding , confidence interval , pediatrics , cumulative incidence , relative risk , demography , survival analysis , environmental health , cohort , sociology

Human immunodeficiency virus (HIV)-infected pregnant women increasingly receive antiretroviral therapy (ART) to prevent mother-to-child transmission (PMTCT). Studies suggest HIV-exposed uninfected (HEU) children face higher mortality than HIV-unexposed children, but most evidence relates to the pre-ART era, breastfeeding of limited duration, and considerable maternal mortality. Maternal ART and prolonged breastfeeding while on ART may improve survival, although this has not been reliably quantified.

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