Open AccessPneumococcal Community-Acquired Pneumonia Detected by Serotype-Specific Urinary Antigen Detection Assays
Author(s) -
Richard G. Wunderink,
Wesley H. Self,
Evan J. Anderson,
R.A. Balk,
Sherene Fakhran,
D. Mark Courtney,
Chao Qi,
Derek J. Williams,
Yuwei Zhu,
Cynthia G. Whitney,
Matthew R. Moore,
Anna M. Bramley,
Seema Jain,
Kathryn M. Edwards,
Carlos G. Grijalva
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix1066
Subject(s) - medicine , pneumonia , community acquired pneumonia , streptococcus pneumoniae , serotype , sputum , pneumococcal pneumonia , procalcitonin , etiology , urinary system , immunology , urine , blood culture , pneumococcal conjugate vaccine , sepsis , microbiology and biotechnology , pathology , antibiotics , biology , tuberculosis
Streptococcus pneumoniae is considered the leading bacterial cause of pneumonia in adults. Yet, it was not commonly detected by traditional culture-based and conventional urinary testing in a recent multicenter etiology study of adults hospitalized with community-acquired pneumonia (CAP). We used novel serotype-specific urinary antigen detection (SSUAD) assays to determine whether pneumococcal cases were missed by traditional testing.
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