Closing in on the Reservoir: Proactive Case Detection in High-Risk Groups as a Strategy to Detect Plasmodium falciparum Asymptomatic Carriers in Cambodia
Author(s) -
Gabriele Rossi,
Lieven Vernaeve,
Rafaël Van den Bergh,
Chea Nguon,
Mark Debackere,
Carme Abello Peiri,
Vuthea Van,
Nimol Khim,
Saorin Kim,
Rotha Eam,
Malen Ken,
Chanra Khean,
Martin De Smet,
Didier Ménard,
Jean-Marie Kindermans
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix1064
Subject(s) - asymptomatic , carriage , population , odds ratio , malaria , medicine , context (archaeology) , attendance , environmental health , plasmodium falciparum , demography , immunology , geography , political science , pathology , sociology , archaeology , law
In the frame of elimination strategies of Plasmodium falciparum (Pf), active case detection has been recommended as complementary approach to the existing passive case detection programs. We trialed a polymerase chain reaction (PCR)-based active detection strategy targeting asymptomatic individuals, named proactive case detection (PACD), with the aim of assessing its feasibility, the extra yield of Pf infections, and the at-risk population for Pf carriage status.
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