Cytomegalovirus DNA Detection by Polymerase Chain Reaction in Cerebrospinal Fluid of Infants With Congenital Infection: Associations With Clinical Evaluation at Birth and Implications for Follow-up
Author(s) -
Walter-Alfredo Goycochea-Valdivia,
Fernando BaqueroArtigao,
Teresa del Rosal,
Marie Antoinette Frick,
Pablo Rojo,
María-Juncal Echeverría,
Antoni NogueraJulián,
X. Bringué,
Jesús SaavedraLozano,
Isabel Vives-Oñós,
Elisenda Moliner,
María-José Cilleruelo,
Irene Cuadrado,
Elena Colino,
Laura Castells Vilella,
Alfredo Tagarro,
Javier Vilas,
Pere SolerPalacín,
Daniel BlázquezGamero
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix105
Subject(s) - medicine , cerebrospinal fluid , cytomegalovirus , human cytomegalovirus , odds ratio , asymptomatic , lumbar puncture , confidence interval , neuroimaging , viral load , polymerase chain reaction , betaherpesvirinae , gastroenterology , pathology , pediatrics , immunology , herpesviridae , viral disease , virus , biochemistry , chemistry , psychiatry , gene
DNA detection of human cytomegalovirus (hCMV) in cerebrospinal fluid (CSF) by polymerase chain reaction (PCR) is a marker of central nervous system (CNS) involvement in congenital hCMV infection (cCMV), but its prognostic value is unknown.
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