Efficacy and Safety of Oseltamivir in Children: Systematic Review and Individual Patient Data Meta-analysis of Randomized Controlled Trials | Zendy

Ryan E. Malosh | Zendy; Emily T. Martin | Zendy; Terho Heikkinen | Zendy; W. Abdullah Brooks | Zendy; Richard J. Whitley | Zendy; Arnold S. Monto | Zendy

Open Access

Efficacy and Safety of Oseltamivir in Children: Systematic Review and Individual Patient Data Meta-analysis of Randomized Controlled Trials

Author(s) -

Ryan E. Malosh,

Emily T. Martin,

Terho Heikkinen,

W. Abdullah Brooks,

Richard J. Whitley,

Arnold S. Monto

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix1040

Subject(s) - medicine , oseltamivir , randomized controlled trial , population , adverse effect , placebo , otitis , confidence interval , pediatrics , surgery , disease , alternative medicine , environmental health , covid-19 , pathology , infectious disease (medical specialty)

Oseltamivir has been used to treat children with influenza for nearly 2 decades, with treatment currently approved for infants aged ≥2 weeks. However, efficacy and safety remain controversial. Newer randomized, placebo-controlled trials (RCTs), not included in previous meta-analyses, can add to the evidence base.

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