Declining Hepatitis C Virus (HCV) Incidence in Dutch Human Immunodeficiency Virus-Positive Men Who Have Sex With Men After Unrestricted Access to HCV Therapy | Zendy

Anne Boerekamps | Zendy; Guido E van den Berk | Zendy; Fanny N. Lauw | Zendy; Eliane M.S. Leyten | Zendy; Marjo E. van Kasteren | Zendy; Arne van Eeden | Zendy; Dirk Posthouwer | Zendy; Mark A. A. Claassen | Zendy; Anton S. M. Dofferhoff | Zendy; D. W. M. Verhagen | Zendy; Wouter F.W. Bierman | Zendy; Kamilla D. Lettinga | Zendy; Frank P. Kroon | Zendy; Corine E. Delsing | Zendy; P. H. P. Groeneveld | Zendy; Robert Soetekouw | Zendy; Edgar J.G. Peters | Zendy; Sebastiaan Hullegie | Zendy; Stephanie Popping | Zendy; David van de Vijver | Zendy; Charles A. Boucher | Zendy; Joop E. Arends | Zendy; Bart Rijnders | Zendy

Open Access

Declining Hepatitis C Virus (HCV) Incidence in Dutch Human Immunodeficiency Virus-Positive Men Who Have Sex With Men After Unrestricted Access to HCV Therapy

Author(s) -

Anne Boerekamps,

Guido E van den Berk,

Fanny N. Lauw,

Eliane M.S. Leyten,

Marjo E. van Kasteren,

Arne van Eeden,

Dirk Posthouwer,

Mark A. A. Claassen,

Anton S. M. Dofferhoff,

D. W. M. Verhagen,

Wouter F.W. Bierman,

Kamilla D. Lettinga,

Frank P. Kroon,

Corine E. Delsing,

P. H. P. Groeneveld,

Robert Soetekouw,

Edgar J.G. Peters,

Sebastiaan Hullegie,

Stephanie Popping,

David van de Vijver,

Charles A. Boucher,

Joop E. Arends,

Bart Rijnders

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix1007

Subject(s) - medicine , hepatitis c virus , virology , incidence (geometry) , hepatitis c , men who have sex with men , virus , viral disease , human immunodeficiency virus (hiv) , ribavirin , hepacivirus , immunology , physics , syphilis , optics

Direct-acting antivirals (DAAa) cure hepatitis C virus (HCV) infections in 95% of infected patients. Modeling studies predict that universal HCV treatment will lead to a decrease in the incidence of new infections but real-life data are lacking. The incidence of HCV among Dutch human immunodeficiency virus (HIV)-positive men who have sex with men (MSM) has been high for >10 years. In 2015 DAAs became available to all Dutch HCV patients and resulted in a rapid treatment uptake in HIV-positive MSM. We assessed whether this uptake was followed by a decrease in the incidence of HCV infections.

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