Limited Utility of Polymerase Chain Reaction in Induced Sputum Specimens for Determining the Causes of Childhood Pneumonia in Resource-Poor Settings: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study | Zendy

Donald M. Thea | Zendy; Phil Seidenberg | Zendy; Daniel E. Park | Zendy; Lawrence Mwananyanda | Zendy; Wei Fu | Zendy; Qiyuan Shi | Zendy; Henry C. Baggett | Zendy; W. Abdullah Brooks | Zendy; Daniel R. Feikin | Zendy; Stephen R. C. Howie | Zendy; Maria Deloria Knoll | Zendy; Karen L. Kotloff | Zendy; Orin S. Levine | Zendy; Shabir A. Madhi | Zendy; Katherine L. O’Brien | Zendy; J. Anthony G. Scott | Zendy; Martín Antonio | Zendy; Juliet O. Awori | Zendy; Vicky L. Baillie | Zendy; Andrea N. DeLuca | Zendy; Amanda J. Driscoll | Zendy; Melissa M. Higdon | Zendy; Lokman Hossain | Zendy; Yasmin Jahan | Zendy; Ruth A. Karron | Zendy; Sidi Kazungu | Zendy; Mengying Li | Zendy; David P. Moore | Zendy; Christian Bottomley | Zendy; Ogochukwu Ofordile | Zendy; Christine Prosperi | Zendy; Ornuma Sangwichian | Zendy; Pongpun Sawatwong | Zendy; Mamadou Sylla | Zendy; Milagritos D. Tapia | Zendy; Scott L. Zeger | Zendy; David R. Murdoch | Zendy; Laura L. Hammitt | Zendy; K. L. O. | Zendy; Ong L | Zendy; M. D. K. | Zendy; Domínguez Rodríguez F | Zendy; A. N. D. | Zendy; A. J. D. | Zendy; Nicholas Fancourt | Zendy; Wu F | Zendy; L. L. H. | Zendy; Mirza Hasanuzzaman | Zendy; E. Wangeci Kagucia | Zendy; R. A. K. | Zendy; Liang Ma | Zendy; Dan Pan | Zendy; C. P. | Zendy; Zhenke Wu | Zendy; Singer Z | Zendy; Nora L. Watson | Zendy; Jane Crawley | Zendy; Don M | Zendy; Bard A | Zendy; Hubert P. Endtz | Zendy; Zaman Khalequ | Zendy; Doli Goswami | Zendy; Liu H | Zendy; Y. J. | Zendy; Hasan Ashraf | Zendy; Shu Hisata | Zendy; Bernard E. Ebruke | Zendy; Antoine Gavoille | Zendy; Jessica McLellan | Zendy; Eunice Machuka | Zendy; Arifin Shamsul | Zendy; Syed M. A. Zaman | Zendy; Grant Mackenzie | Zendy; J. A. G. S. | Zendy; Jo A | Zendy; Szymanski Christine M. | Zendy; Alice Kamau | Zendy; S. K. | Zendy; Micah Silaba Ominde | Zendy; K. L. K. | Zendy; M. D. T. | Zendy; Samba O. Sow | Zendy; S Michael Crawford | Zendy; Boubou Tamboura | Zendy; Uma Onwuchekwa | Zendy; Nana Kourouma | Zendy; Aliou Touré | Zendy; SALAMA M | Zendy; D. P. M. | Zendy; Peter V. Adrian | Zendy; von Loeffelholz B | Zendy; Locadiah Kuwanda | Zendy; Azwifarwi Mudau | Zendy; Michelle J. Groome | Zendy; Nasreen Mahomed | Zendy; H. C. B. | Zendy; Somsak Thamthitiwat | Zendy; Susan A. Maloney | Zendy; Charatdao Bunthi | Zendy; Julia Rhodes | Zendy; S Padmalatha | Zendy; Pasakorn Akarasewi | Zendy; Doi T | Zendy; L. M. | Zendy; James Chipeta | Zendy; James Mwansa | Zendy; Somwe Wa Somwe | Zendy; Geoffrey Kwenda | Zendy; Trevor P. Anderson | Zendy; Joanne Mitchell | Zendy

Open Access

Limited Utility of Polymerase Chain Reaction in Induced Sputum Specimens for Determining the Causes of Childhood Pneumonia in Resource-Poor Settings: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study

Author(s) -

Donald M. Thea,

Phil Seidenberg,

Daniel E. Park,

Lawrence Mwananyanda,

Wei Fu,

Qiyuan Shi,

Henry C. Baggett,

W. Abdullah Brooks,

Daniel R. Feikin,

Stephen R. C. Howie,

Maria Deloria Knoll,

Karen L. Kotloff,

Orin S. Levine,

Shabir A. Madhi,

Katherine L. O’Brien,

J. Anthony G. Scott,

Martín Antonio,

Juliet O. Awori,

Vicky L. Baillie,

Andrea N. DeLuca,

Amanda J. Driscoll,

Melissa M. Higdon,

Lokman Hossain,

Yasmin Jahan,

Ruth A. Karron,

Sidi Kazungu,

Mengying Li,

David P. Moore,

Christian Bottomley,

Ogochukwu Ofordile,

Christine Prosperi,

Ornuma Sangwichian,

Pongpun Sawatwong,

Mamadou Sylla,

Milagritos D. Tapia,

Scott L. Zeger,

David R. Murdoch,

Laura L. Hammitt,

K. L. O.,

Ong L,

M. D. K.,

Domínguez Rodríguez F,

A. N. D.,

A. J. D.,

Nicholas Fancourt,

Wu F,

L. L. H.,

Mirza Hasanuzzaman,

E. Wangeci Kagucia,

R. A. K.,

Liang Ma,

Dan Pan,

C. P.,

Zhenke Wu,

Singer Z,

Nora L. Watson,

Jane Crawley,

Don M,

Bard A,

Hubert P. Endtz,

Zaman Khalequ,

Doli Goswami,

Liu H,

Y. J.,

Hasan Ashraf,

Shu Hisata,

Bernard E. Ebruke,

Antoine Gavoille,

Jessica McLellan,

Eunice Machuka,

Arifin Shamsul,

Syed M. A. Zaman,

Grant Mackenzie,

J. A. G. S.,

Jo A,

Szymanski Christine M.,

Alice Kamau,

S. K.,

Micah Silaba Ominde,

K. L. K.,

M. D. T.,

Samba O. Sow,

S Michael Crawford,

Boubou Tamboura,

Uma Onwuchekwa,

Nana Kourouma,

Aliou Touré,

SALAMA M,

D. P. M.,

Peter V. Adrian,

von Loeffelholz B,

Locadiah Kuwanda,

Azwifarwi Mudau,

Michelle J. Groome,

Nasreen Mahomed,

H. C. B.,

Somsak Thamthitiwat,

Susan A. Maloney,

Charatdao Bunthi,

Julia Rhodes,

S Padmalatha,

Pasakorn Akarasewi,

Doi T,

L. M.,

James Chipeta,

James Mwansa,

Somwe Wa Somwe,

Geoffrey Kwenda,

Trevor P. Anderson,

Joanne Mitchell

Publication year - 2017

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/cix098

Subject(s) - pneumonia , medicine , sputum , etiology , respiratory disease , radiography , pathology , surgery , lung , tuberculosis

Sputum examination can be useful in diagnosing the cause of pneumonia in adults but is less well established in children. We sought to assess the diagnostic utility of polymerase chain reaction (PCR) for detection of respiratory viruses and bacteria in induced sputum (IS) specimens from children hospitalized with severe or very severe pneumonia.

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