Microscopic Analysis and Quality Assessment of Induced Sputum From Children With Pneumonia in the PERCH Study
Author(s) -
David R. Murdoch,
Susan C. Morpeth,
Laura L. Hammitt,
Amanda J. Driscoll,
Nora L. Watson,
Henry C. Baggett,
W. Abdullah Brooks,
Maria Deloria Knoll,
Daniel R. Feikin,
Karen L. Kotloff,
Orin S. Levine,
Shabir A. Madhi,
Katherine L. O’Brien,
J. Anthony G. Scott,
Donald M. Thea,
Dilruba Ahmed,
Juliet O. Awori,
Andrea N. DeLuca,
Bernard E. Ebruke,
Melissa M. Higdon,
Possawat Jorakate,
Ruth A. Karron,
Sidi Kazungu,
Geoffrey Kwenda,
Lokman Hossain,
Sirirat Makprasert,
David P. Moore,
Azwifarwi Mudau,
John Mwaba,
Sandra Panchalingam,
Daniel E. Park,
Christine Prosperi,
Rasheed Salaudeen,
Aliou Touré,
Scott L. Zeger,
Stephen R. C. Howie,
Nicholas Fancourt,
Wei Fu,
E. Wangeci Kagucia,
Mengying Li,
Zhenke Wu,
Jane Crawley,
Hubert P. Endtz,
Khalequ Zaman,
Doli Goswami,
Yasmin Jahan,
Hasan Ashraf,
Martín Antonio,
Jessica McLellan,
Eunice Machuka,
Arifin Shamsul,
Syed M. A. Zaman,
Grant Mackenzie,
Alice Kamau,
Micah Silab Ominde,
Milagritos D. Tapia,
Samba O. Sow,
Mamadou Sylla,
Boubou Tamboura,
Uma Onwuchekwa,
Nana Kourouma,
Peter V. Adrian,
Vicky L. Baillie,
Locadiah Kuwanda,
Michelle J. Groome,
Nasreen Mahomed,
Somsak Thamthitiwat,
Susan A. Maloney,
Charatdao Bunthi,
Julia Rhodes,
Pongpun Sawatwong,
Pasakorn Akarasewi,
Lawrence Mwananyanda,
James Chipeta,
Phil Seidenberg,
James Mwansa,
Somwe Wa Somwe,
Trevor P. Anderson,
Joanne Mitchell
Publication year - 2017
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/cix083
Subject(s) - sputum , medicine , pneumonia , respiratory tract , respiratory tract infections , respiratory system , pathology , microbiology and biotechnology , immunology , biology , tuberculosis
It is standard practice for laboratories to assess the cellular quality of expectorated sputum specimens to check that they originated from the lower respiratory tract. The presence of low numbers of squamous epithelial cells (SECs) and high numbers of polymorphonuclear (PMN) cells are regarded as indicative of a lower respiratory tract specimen. However, these quality ratings have never been evaluated for induced sputum specimens from children with suspected pneumonia.
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