Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report | Zendy

Alessandro Soria | Zendy; Claudia Alteri | Zendy; Gabriella Scarlatti | Zendy; Ada Bertoli | Zendy; Monica Tolazzi | Zendy; E Balestra | Zendy; Maria Concetta Bellocchi | Zendy; Fabio Continenza | Zendy; Luca Carioti | Zendy; Mara Biasin | Zendy; Daria Trabattoni | Zendy; Alessandra Bandera | Zendy; Francesca CeccheriniSilberstein | Zendy; Carlo Federico Perno | Zendy; Andrea Gori | Zendy

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Occupational HIV infection in a research laboratory with unknown mode of transmission: a case report

Author(s) -

Alessandro Soria,

Claudia Alteri,

Gabriella Scarlatti,

Ada Bertoli,

Monica Tolazzi,

E Balestra,

Maria Concetta Bellocchi,

Fabio Continenza,

Luca Carioti,

Mara Biasin,

Daria Trabattoni,

Alessandra Bandera,

Francesca CeccheriniSilberstein,

Carlo Federico Perno,

Andrea Gori

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw851

Subject(s) - biosafety , medicine , transmission (telecommunications) , virology , human immunodeficiency virus (hiv) , clone (java method) , occupational exposure , replication (statistics) , genome , environmental health , biology , genetics , pathology , gene , electrical engineering , engineering

A laboratory worker was infected with human immunodeficiency virus (HIV) type 1 in a biosafety level 2 containment facility, without any apparent breach. Through full-genome sequencing and phylogenetic analyses, we could identify the source of infection in a replication-competent clone that unknowingly contaminated a safe experiment. Mode of transmission remains unclear. Caution is warranted when handling HIV-derived constructs.

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