Novel Clinical and Pathologic Findings in a Heartland Virus–Associated Death | Zendy

MaryMargaret A. Fill | Zendy; Margaret Compton | Zendy; Edward C. McDonald | Zendy; Abelardo C. Moncayo | Zendy; John R. Dunn | Zendy; William Schaffner | Zendy; Julu Bhatnagar | Zendy; Sherif R. Zaki | Zendy; Timothy F. Jones | Zendy; WunJu Shieh | Zendy

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Novel Clinical and Pathologic Findings in a Heartland Virus–Associated Death

Author(s) -

MaryMargaret A. Fill,

Margaret Compton,

Edward C. McDonald,

Abelardo C. Moncayo,

John R. Dunn,

William Schaffner,

Julu Bhatnagar,

Sherif R. Zaki,

Timothy F. Jones,

WunJu Shieh

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw766

Subject(s) - medicine , virus , cause of death , virology , pathology , immunology , disease

We describe an investigation into a Heartland virus (HRTV)-associated death in Tennessee with novel clinical and pathologic findings. HRTV can cause rapidly fatal, widely disseminated infection with multisystem organ failure in patients without substantial comorbidities. We identified viral antigen in multiple organ tissues where it was not detected previously.

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