Transmissibility of Clostridium difficile without contact isolation: results from a prospective observational study with 451 patients | Zendy

Andreas F. Widmer | Zendy; Reno Frei | Zendy; Stefan Erb | Zendy; Anne Stranden | Zendy; Ed J. Kuijper | Zendy; Cornelis W. Knetsch | Zendy; Sarah TschudinSutter | Zendy

Open Access

Transmissibility of Clostridium difficile without contact isolation: results from a prospective observational study with 451 patients

Author(s) -

Andreas F. Widmer,

Reno Frei,

Stefan Erb,

Anne Stranden,

Ed J. Kuijper,

Cornelis W. Knetsch,

Sarah TschudinSutter

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw758

Subject(s) - clostridium difficile , medicine , transmission (telecommunications) , outbreak , index case , attack rate , infection control , contact tracing , polymerase chain reaction , isolation (microbiology) , microbiology and biotechnology , virology , surgery , biology , covid-19 , disease , infectious disease (medical specialty) , antibiotics , biochemistry , electrical engineering , gene , engineering

Contact precautions are recommended by health authorities in Europe and the United States for patients with Clostridium difficile infection (CDI). Recently, the significance of nosocomial transmission has been challenged by screening on admission studies and whole-genome sequencing, providing evidence for an endogenous source of C. difficile. We discontinued contact precautions for patients with CDI, except for patients infected with hypervirulent ribotypes or with stool incontinence, to determine the rate of transmission.

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