Fixed-Dose Artesunate–Amodiaquine Combination vs Chloroquine for Treatment of Uncomplicated Blood Stage P. vivax Infection in the Brazilian Amazon: An Open-Label Randomized, Controlled Trial
Author(s) -
André M. Siqueira,
Aline Alencar,
Gisely Cardoso de Melo,
Belisa L. Magalhães,
Kim Machado,
Aristóteles C. Alencar Filho,
Andrea Kuehn,
Marly M. Marques,
Monica Costa Manso,
Ingrid Felger,
José Luiz Fernandes Vieira,
Valérie Lameyre,
Cláudio Tadeu DanielRibeiro,
Marcus Lacerda
Publication year - 2016
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciw706
Subject(s) - medicine , artesunate , fixed dose combination , randomized controlled trial , amodiaquine , adverse effect , artemisinin , plasmodium vivax , gastroenterology , surgery , malaria , plasmodium falciparum , immunology
Despite increasing evidence of the development of Plasmodium vivax chloroquine (CQ) resistance, there have been no trials comparing its efficacy with that of artemisinin-based combination therapies (ACTs) in Latin America.
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