Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection | Zendy

Irini Sereti | Zendy; Shelly J. Krebs | Zendy; Nittaya Phanuphak | Zendy; James L. K. Fletcher | Zendy; Bonnie M. Slike | Zendy; Suteeraporn Pinyakorn | Zendy; Robert J. O’Connell | Zendy; Adam Rupert | Zendy; Nicolas Chomont | Zendy; Victor Valcour | Zendy; Jérôme H. Kim | Zendy; Merlin L. Robb | Zendy; Nelson L. Michael | Zendy; Daniel C. Douek | Zendy; Jintanat Ananworanich | Zendy; Netanya S. Utay | Zendy

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Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

Author(s) -

Irini Sereti,

Shelly J. Krebs,

Nittaya Phanuphak,

James L. K. Fletcher,

Bonnie M. Slike,

Suteeraporn Pinyakorn,

Robert J. O’Connell,

Adam Rupert,

Nicolas Chomont,

Victor Valcour,

Jérôme H. Kim,

Merlin L. Robb,

Nelson L. Michael,

Daniel C. Douek,

Jintanat Ananworanich,

Netanya S. Utay

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw683

Subject(s) - medicine , immunology , inflammation , systemic inflammation , biomarker , tumor necrosis factor alpha , acute phase protein , c reactive protein , biology , biochemistry

Serious non-AIDS events cause substantial disease and death despite human immunodeficiency virus (HIV) suppression with antiretroviral therapy (ART). Biomarkers of inflammation, coagulation cascade activation, and fibrosis predict these end-organ events. We aimed to determine whether ART initiation during acute HIV infection would attenuate changes in these biomarker levels.

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