Detection of Circulating Mucorales DNA in Critically Ill Burn Patients: Preliminary Report of a Screening Strategy for Early Diagnosis and Treatment | Zendy

Matthieu Legrand | Zendy; Maud GitsMuselli | Zendy; Louis Boutin | Zendy; Dea García-Hermoso | Zendy; Véronique Maurel | Zendy; Sabri Soussi | Zendy; Mourad Benyamina | Zendy; Axelle Ferry | Zendy; Maïté Chaussard | Zendy; Samia Hamane | Zendy; Blandine Denis | Zendy; Sophie Touratier | Zendy; Nicolas Guigue | Zendy; Émilie Fréalle | Zendy; M. Jeanne | Zendy; Jean-Vivien Shaal | Zendy; C. Soler | Zendy; Maurice Mimoun | Zendy; Marc Chaouat | Zendy; Matthieu Lafaurie | Zendy; Alexandre Mebazaa | Zendy; Stéphane Bretagne | Zendy; Alexandre Alanio | Zendy

Open Access

Detection of Circulating Mucorales DNA in Critically Ill Burn Patients: Preliminary Report of a Screening Strategy for Early Diagnosis and Treatment

Author(s) -

Matthieu Legrand,

Maud GitsMuselli,

Louis Boutin,

Dea García-Hermoso,

Véronique Maurel,

Sabri Soussi,

Mourad Benyamina,

Axelle Ferry,

Maïté Chaussard,

Samia Hamane,

Blandine Denis,

Sophie Touratier,

Nicolas Guigue,

Émilie Fréalle,

M. Jeanne,

Jean-Vivien Shaal,

C. Soler,

Maurice Mimoun,

Marc Chaouat,

Matthieu Lafaurie,

Alexandre Mebazaa,

Stéphane Bretagne,

Alexandre Alanio

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw563

Subject(s) - medicine , clinical endpoint , critically ill , retrospective cohort study , mucormycosis , burn center , mortality rate , surgery , clinical trial , emergency medicine , poison control

Invasive wound mucormycosis (IWM) is associated with an extremely poor outcome among critically ill burn patients. We describe the detection of circulating Mucorales DNA (cmDNA) for the early diagnosis of IWM in those patients and report the potential value of detecting cmDNA for treatment guidance.

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