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No Evidence of Reactivation of Hepatitis B Virus Among Patients Treated With Ledipasvir-Sofosbuvir for Hepatitis C Virus Infection: Table 1.
Author(s) -
Mark Sulkowski,
WanLong Chuang,
JiaHorng Kao,
Jenny C. Yang,
Bing Gao,
Diana M. Brainard,
Kwang–Hyub Han,
Edward Gane
Publication year - 2016
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciw507
Subject(s) - medicine , sofosbuvir , ledipasvir , virology , hepatitis b virus , hepatitis c virus , hepatitis c , virus , gastroenterology , ribavirin
Postmarketing cases of hepatitis B virus (HBV) reactivation during hepatitis C treatment have been reported. We analyzed serum samples from patients in a clinical trial of ledipasvir-sofosbuvir in Taiwan and Korea. Of the 173 patients enrolled, 103 (60%) had been previously infected with HBV. None showed evidence of HBV reactivation.

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