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Mass drug administration (MDA) with praziquantel is the cornerstone of schistosomiasis control in sub-Saharan Africa. The effectiveness of this strategy is dependent on the continued high efficacy of praziquantel; however, drug efficacy is rarely monitored using appropriate statistical approaches that can detect early signs of wane.

Reduced Efficacy of Praziquantel AgainstSchistosoma mansoniIs Associated With Multiple Rounds of Mass Drug Administration