Initiation of Antiretroviral Therapy During Acute HIV-1 Infection Leads to a High Rate of Nonreactive HIV Serology | Zendy

Mark de Souza | Zendy; Suteeraporn Pinyakorn | Zendy; Siriwat Akapirat | Zendy; Supanit Pattanachaiwit | Zendy; James L. K. Fletcher | Zendy; Nitiya Chomchey | Zendy; Eugène Kroon | Zendy; Sasiwimol Ubolyam | Zendy; Nelson L. Michael | Zendy; Merlin L. Robb | Zendy; Praphan Phanuphak | Zendy; Jérôme H. Kim | Zendy; Nittaya Phanuphak | Zendy; Jintanat Ananworanich | Zendy

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Initiation of Antiretroviral Therapy During Acute HIV-1 Infection Leads to a High Rate of Nonreactive HIV Serology

Author(s) -

Mark de Souza,

Suteeraporn Pinyakorn,

Siriwat Akapirat,

Supanit Pattanachaiwit,

James L. K. Fletcher,

Nitiya Chomchey,

Eugène Kroon,

Sasiwimol Ubolyam,

Nelson L. Michael,

Merlin L. Robb,

Praphan Phanuphak,

Jérôme H. Kim,

Nittaya Phanuphak,

Jintanat Ananworanich

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw365

Subject(s) - medicine , antibody , serology , antiretroviral therapy , human immunodeficiency virus (hiv) , immunology , virology , viral load

Third- and fourth-generation immunoassays (IAs) are widely used in the diagnosis of human immunodeficiency virus (HIV) infection. Antiretroviral therapy (ART) during acute HIV infection (AHI) may impact HIV-specific antibodies, with failure to develop antibody or seroreversion. We report on the ability of diagnostic tests to detect HIV-specific antibodies in Thai participants initiating ART during AHI.

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