Clinical and Epidemiological Evidence of the Red Queen Hypothesis in Pneumococcal Serotype Dynamics | Zendy

Chris Stockmann | Zendy; Krow Ampofo | Zendy; Andrew T. Pavia | Zendy; Anne J. Blaschke | Zendy; Edward O. Mason | Zendy; Angela P. Presson | Zendy; Larry J. Forney | Zendy; Carrie L. Byington | Zendy

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Clinical and Epidemiological Evidence of the Red Queen Hypothesis in Pneumococcal Serotype Dynamics

Author(s) -

Chris Stockmann,

Krow Ampofo,

Andrew T. Pavia,

Anne J. Blaschke,

Edward O. Mason,

Angela P. Presson,

Larry J. Forney,

Carrie L. Byington

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw357

Subject(s) - serotype , pneumococcal conjugate vaccine , coevolution , pneumococcal disease , herd immunity , medicine , vaccination , streptococcus pneumoniae , biology , demography , immunology , evolutionary biology , genetics , sociology , bacteria

The Red Queen hypothesis is an evolutionary theory that describes the reciprocal coevolution of competing species. We sought to study whether introduction of the 7- and 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13, respectively) altered pneumococcal serotype dynamics among children with invasive pneumococcal disease (IPD) as predicted by the Red Queen hypothesis.

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