Clinical Implications for Children Born With Congenital Cytomegalovirus Infection Following a Negative Amniocentesis | Zendy

Efraim Bilavsky | Zendy; Joseph Pardo | Zendy; Joseph Attias | Zendy; Itzhak Levy | Zendy; JeanFrançois Magny | Zendy; Y. Ville | Zendy; Marianne LeruezVille | Zendy; Jacob Amir | Zendy

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Clinical Implications for Children Born With Congenital Cytomegalovirus Infection Following a Negative Amniocentesis

Author(s) -

Efraim Bilavsky,

Joseph Pardo,

Joseph Attias,

Itzhak Levy,

JeanFrançois Magny,

Y. Ville,

Marianne LeruezVille,

Jacob Amir

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw237

Subject(s) - medicine , amniocentesis , cytomegalovirus , cytomegalovirus infections , betaherpesvirinae , pediatrics , pregnancy , human cytomegalovirus , herpesviridae , obstetrics , viral disease , virology , prenatal diagnosis , fetus , virus , genetics , biology

Recently, congenital cytomegalovirus (cCMV) infection was reported irrespective of a negative amniotic fluid prenatal analysis for cytomegalovirus (CMV). The question of whether this phenomenon represents low sensitivity of the test or late development of fetal infection (after amniocentesis) was discussed, but not answered. However, if late transmission is the rule, then infants born with cCMV after negative amniocentesis would be expected to carry better prognosis than those who tested positive.

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