A Randomized Trial of Clindamycin Versus Trimethoprim-sulfamethoxazole for Uncomplicated Wound Infection
Author(s) -
David A. Talan,
Frank LoVecchio,
Fredrick M. Abrahamian,
David J. Karras,
Mark T. Steele,
Richard E. Rothman,
Anusha Krishnadasan,
William R. Mower,
Rebecca Hoagland,
Gregory J. Moran
Publication year - 2016
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciw177
Subject(s) - medicine , clindamycin , trimethoprim , sulfamethoxazole , confidence interval , adverse effect , population , randomized controlled trial , antibiotics , surgery , staphylococcus aureus , microbiology and biotechnology , biology , genetics , environmental health , bacteria
With the emergence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) in the United States, visits for skin infections greatly increased. Staphylococci and streptococci are considered predominant causes of wound infections. Clindamycin and trimethoprim-sulfamethoxazole (TMP-SMX) are commonly prescribed, but the efficacy of TMP-SMX has been questioned.
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