Test of Cure for Anogenital Gonorrhoea Using Modern RNA-Based and DNA-Based Nucleic Acid Amplification Tests: A Prospective Cohort Study
Author(s) -
Carolien M. Wind,
Maarten F. Schim van der Loeff,
Magnus Unemo,
Rob Schuurman,
Alje P. van Dam,
Henry J.C. de Vries
Publication year - 2016
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/ciw141
Subject(s) - medicine , nucleic acid amplification tests , azithromycin , prospective cohort study , cohort , clearance , doxycycline , chlamydia , neisseria gonorrhoeae , rna , virology , chlamydia trachomatis , antibiotics , immunology , microbiology and biotechnology , biology , urology , biochemistry , gene
The use of nucleic acid amplification tests (NAATs) to diagnose Neisseria gonorrhoeae infections complicates the performance of a test of cure (TOC) to monitor treatment failure, if this is indicated. As evidence for the timing of TOC using modern NAATs is limited, we performed a prospective cohort study to assess time to clearance when using modern RNA- and DNA-based NAATs.
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