Cysticidal Efficacy of Combined Treatment With Praziquantel and Albendazole for Parenchymal Brain Cysticercosis | Zendy

Héctor H. Garcı́a | Zendy; Andrés G. Lescano | Zendy; Isidro Gonzáles | Zendy; Javier A. Bustos | Zendy; E. Javier Pretell | Zendy; John Horton | Zendy; Herbert Saavedra | Zendy; Armando E. González | Zendy; Robert H. Gilman | Zendy

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Cysticidal Efficacy of Combined Treatment With Praziquantel and Albendazole for Parenchymal Brain Cysticercosis

Author(s) -

Héctor H. Garcı́a,

Andrés G. Lescano,

Isidro Gonzáles,

Javier A. Bustos,

E. Javier Pretell,

John Horton,

Herbert Saavedra,

Armando E. González,

Robert H. Gilman

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw134

Subject(s) - medicine , praziquantel , albendazole , cysticercosis , antiparasitic agent , pharmacokinetics , neurocysticercosis , pharmacology , carbamazepine , concomitant , gastroenterology , surgery , pathology , immunology , epilepsy , schistosomiasis , psychiatry , helminths

The efficacy of current antiparasitic treatment for cerebral Taenia solium cysticercosis with either albendazole (ABZ) or praziquantel (PZQ) is suboptimal. A recent study demonstrated that combining these 2 antiparasitic drugs improves antiparasitic efficacy. We present here the parasiticidal efficacy data obtained during a previous phase II pharmacokinetic study that compared combined ABZ plus PZQ with ABZ alone.

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