Determinants of a Low CD4/CD8 Ratio in HIV-1–Infected Individuals Despite Long-term Viral Suppression | Zendy

Fabienne Caby | Zendy; Amélie Guihot | Zendy; Sidonie Lambert-Niclot | Zendy; Marguerite Guiguet | Zendy; David Boutolleau | Zendy; Rachid Agher | Zendy; MarcAntoine Valantin | Zendy; Roland Tubiana | Zendy; Vincent Cálvez | Zendy; AnneGeneviève Marcelin | Zendy; Guislaine Carcelain | Zendy; Brigitte Autran | Zendy; Dominique Costagliola | Zendy; Christine Katlama | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Determinants of a Low CD4/CD8 Ratio in HIV-1–Infected Individuals Despite Long-term Viral Suppression

Author(s) -

Fabienne Caby,

Amélie Guihot,

Sidonie Lambert-Niclot,

Marguerite Guiguet,

David Boutolleau,

Rachid Agher,

MarcAntoine Valantin,

Roland Tubiana,

Vincent Cálvez,

AnneGeneviève Marcelin,

Guislaine Carcelain,

Brigitte Autran,

Dominique Costagliola,

Christine Katlama

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw076

Subject(s) - interquartile range , medicine , odds ratio , cd4 cd8 ratio , viral load , confidence interval , cd8 , immunology , gastroenterology , immune system , human immunodeficiency virus (hiv) , lymphocyte subsets

A low CD4/CD8 ratio in human immunodeficiency virus (HIV)-infected individuals despite effective antiretroviral therapy (ART) reflects ongoing immune activation and has been linked to a higher risk of non-AIDS morbidity and mortality. Our aim was to describe the proportion of individuals with a persistent CD4/CD8 ratio <1 despite long-term viral suppression and to determine associated risk factors.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research