Applicability of Hepatitis C Virus RNA Viral Load Thresholds for 8-Week Treatments in Patients With Chronic Hepatitis C Virus Genotype 1 Infection | Zendy

Johannes Vermehren | Zendy; Benjamin Maasoumy | Zendy; Raoel Maan | Zendy; Gavin Cloherty | Zendy; C. Berkowski | Zendy; Jordan J. Feld | Zendy; Markus Cornberg | Zendy; JeanMichel Pawlotsky | Zendy; Stefan Zeuzem | Zendy; Michael P. Manns | Zendy; Christoph Sarrazin | Zendy; Heiner Wedemeyer | Zendy

Open Access

Applicability of Hepatitis C Virus RNA Viral Load Thresholds for 8-Week Treatments in Patients With Chronic Hepatitis C Virus Genotype 1 Infection

Author(s) -

Johannes Vermehren,

Benjamin Maasoumy,

Raoel Maan,

Gavin Cloherty,

C. Berkowski,

Jordan J. Feld,

Markus Cornberg,

JeanMichel Pawlotsky,

Stefan Zeuzem,

Michael P. Manns,

Christoph Sarrazin,

Heiner Wedemeyer

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw061

Subject(s) - medicine , viral load , hepatitis c virus , chronic hepatitis , virus , genotype , gastroenterology , virology , hepatitis c , interferon , immunology , biology , biochemistry , gene

Interferon-free treatment of chronic hepatitis C virus (HCV) genotype 1 infection may be shortened to 8 weeks in treatment-naive, noncirrhotic patients with baseline HCV RNA levels of <4 or <6 million (M) IU/mL based on post-hoc analyses of phase 3 trial data. The applicability of these viral load thresholds in clinical practice is unknown.

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