Protective Effect of Contemporary Pertussis Vaccines: A Systematic Review and Meta-analysis | Zendy

T. Roice Fulton | Zendy; Varun K. Phadke | Zendy; Walter A. Orenstein | Zendy; Alan R. Hinman | Zendy; Wayne D. Johnson | Zendy; Saad B. Omer | Zendy

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Protective Effect of Contemporary Pertussis Vaccines: A Systematic Review and Meta-analysis

Author(s) -

T. Roice Fulton,

Varun K. Phadke,

Walter A. Orenstein,

Alan R. Hinman,

Wayne D. Johnson,

Saad B. Omer

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw051

Subject(s) - medicine , pertussis vaccine , meta analysis , vaccine efficacy , confidence interval , whooping cough , pediatrics , immunology , vaccination , immunization , immune system

Acellular pertussis (aP) and whole-cell (wP) pertussis vaccines are presumed to have similar short-term (<3 years after completion of the primary series) efficacy. However, vaccine effect varies between individual pertussis vaccine formulations, and many originally studied formulations are now unavailable. An updated analysis of the short-term protective effect of pertussis vaccines limited to formulations currently on the market in developed countries is needed.

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