Whole-Genome Sequencing Reveals the Origin and Rapid Evolution of an Emerging Outbreak Strain ofStreptococcus pneumoniae12F | Zendy

Xianding Deng | Zendy; Gisele Peirano | Zendy; Erin Schillberg | Zendy; Tony Mazzulli | Zendy; Scott D. GrayOwen | Zendy; John Wylie | Zendy; D. Ashley Robinson | Zendy; Salaheddin M. Mahmud | Zendy; Dylan R. Pillai | Zendy

Open Access

Whole-Genome Sequencing Reveals the Origin and Rapid Evolution of an Emerging Outbreak Strain ofStreptococcus pneumoniae12F

Author(s) -

Xianding Deng,

Gisele Peirano,

Erin Schillberg,

Tony Mazzulli,

Scott D. GrayOwen,

John Wylie,

D. Ashley Robinson,

Salaheddin M. Mahmud,

Dylan R. Pillai

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw050

Subject(s) - outbreak , streptococcus pneumoniae , biology , drug resistance , serotype , genome , strain (injury) , virulence , clone (java method) , pneumolysin , whole genome sequencing , virology , microbiology and biotechnology , genetics , gene , antibiotics , anatomy

Streptococcus pneumoniaeis a major cause of community-acquired pneumonia and septicemia in adults. The global drug-susceptible capsular serotype 12F, clonal complex 218 caused several outbreaks in the United States between 1989 and 2008, as well as a recent large outbreak in Manitoba, Canada, that resulted in 36 cases of septicemia and 3 deaths. The evolutionary origin of the Canadian outbreak strain and its relationship to the historical US outbreak strains are not known.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research