Surgery as an Adjunctive Treatment for Multidrug-Resistant Tuberculosis: An Individual Patient Data Metaanalysis | Zendy

Gregory J. Fox | Zendy; Carole D. Mitnick | Zendy; Andrea Benedetti | Zendy; Edward D. Chan | Zendy; Mercedes C. Becerra | Zendy; ChenYuan Chiang | Zendy; Salmaan Keshavjee | Zendy; WonJung Koh | Zendy; Yuji Shiraishi | Zendy; Piret Viiklepp | Zendy; JaeJoon Yim | Zendy; Geoffrey Pasvol | Zendy; J. Robert | Zendy; Tae Sun Shim | Zendy; Sonya Shin | Zendy; Dick Menzies | Zendy

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Surgery as an Adjunctive Treatment for Multidrug-Resistant Tuberculosis: An Individual Patient Data Metaanalysis

Author(s) -

Gregory J. Fox,

Carole D. Mitnick,

Andrea Benedetti,

Edward D. Chan,

Mercedes C. Becerra,

ChenYuan Chiang,

Salmaan Keshavjee,

WonJung Koh,

Yuji Shiraishi,

Piret Viiklepp,

JaeJoon Yim,

Geoffrey Pasvol,

J. Robert,

Tae Sun Shim,

Sonya Shin,

Dick Menzies

Publication year - 2016

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/ciw002

Subject(s) - medicine , tuberculosis , multiple drug resistance , adjunctive treatment , surgery , drug resistance , biology , pathology , microbiology and biotechnology

Medical treatment for multidrug-resistant (MDR)-tuberculosis is complex, toxic, and associated with poor outcomes. Surgical lung resection may be used as an adjunct to medical therapy, with the intent of reducing bacterial burden and improving cure rates. We conducted an individual patient data metaanalysis to evaluate the effectiveness of surgery as adjunctive therapy for MDR-tuberculosis.

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