Updated US and European Dose Recommendations for Intravenous Colistin: How Do They Perform?
Author(s) -
Roger L. Nation,
Samira M. Garonzik,
Jian Li,
Visanu Thamlikitkul,
Evangelos J. GiamarellosBourboulis,
David L. Paterson,
John Turnidge,
Alan Forrest,
Fernanda P. Silveira
Publication year - 2015
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/civ964
Subject(s) - medicine , colistin , food and drug administration , intensive care medicine , drug , pharmacology , antibiotics , microbiology and biotechnology , biology
The US Food and Drug Administration (FDA) and European Medicines Agency (EMA) have approved updated dose recommendations for intravenous colistin in patients with various degrees of renal function. We assessed the recommendations in relation to their ability to achieve clinically relevant plasma colistin concentrations.
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