Safety and Efficacy of Intermittent Intravenous Administration of High-Dose Micafungin | Zendy

Dionysios Neofytos | Zendy; Yao-Ting Huang | Zendy; Kimberly M. Cheng | Zendy; Nina Cohen | Zendy; MiguelAngel Perales | Zendy; Juliet N. Barker | Zendy; Sergio Giralt | Zendy; Ann A. Jakubowski | Zendy; Genovefa A. Papanicolaou | Zendy

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Safety and Efficacy of Intermittent Intravenous Administration of High-Dose Micafungin

Author(s) -

Dionysios Neofytos,

Yao-Ting Huang,

Kimberly M. Cheng,

Nina Cohen,

MiguelAngel Perales,

Juliet N. Barker,

Sergio Giralt,

Ann A. Jakubowski,

Genovefa A. Papanicolaou

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ818

Subject(s) - micafungin , medicine , dosing , liver function , adverse effect , renal function , gastroenterology , transplantation , liver function tests , liver transplantation , regimen , pharmacology , voriconazole , antifungal , dermatology

The use of mold-active azoles for antifungal prophylaxis after allogeneic stem cell transplantation (SCT) is hindered by adverse events and drug-drug interactions. Higher doses of echinocandins administered intermittently may be an alternative in this setting.

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