The Role of Echinocandins in Candida Biofilm–Related Vascular Catheter Infections: In Vitro and In Vivo Model Systems | Zendy

Mahmoud A. Ghannoum | Zendy; Emmanuel Roilides | Zendy; Aspasia Katragkou | Zendy; Vidmantas Petraitis | Zendy; Thomas J. Walsh | Zendy

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The Role of Echinocandins in Candida Biofilm–Related Vascular Catheter Infections: In Vitro and In Vivo Model Systems

Author(s) -

Mahmoud A. Ghannoum,

Emmanuel Roilides,

Aspasia Katragkou,

Vidmantas Petraitis,

Thomas J. Walsh

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ815

Subject(s) - echinocandins , in vivo , biofilm , medicine , in vitro , central venous catheter , catheter , microbiology and biotechnology , pathogenesis , bloodstream infection , candida infections , intensive care medicine , candida albicans , immunology , biology , antifungal , bacteria , voriconazole , surgery , caspofungin , biochemistry , genetics , dermatology

Candida biofilm-associated infections of central venous catheters are a challenging therapeutic problem. Recent in vitro and in vivo studies of the structure, formation, pathogenesis, and treatment establish a rationale for new approaches to management of these tenacious infections.

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