Combination of Vancomycin and β-Lactam Therapy for Methicillin-ResistantStaphylococcus aureusBacteremia: A Pilot Multicenter Randomized Controlled Trial | Zendy

Joshua S. Davis | Zendy; Archana Sud | Zendy; Matthew O’Sullivan | Zendy; James O. Robinson | Zendy; Patricia Ferguson | Zendy; Hong Foo | Zendy; Sebastiaan J. van Hal | Zendy; Anna P. Ralph | Zendy; Benjamin P. Howden | Zendy; Paula Binks | Zendy; Adrienne Kirby | Zendy; Steven Y. C. Tong | Zendy

Open Access

Combination of Vancomycin and β-Lactam Therapy for Methicillin-ResistantStaphylococcus aureusBacteremia: A Pilot Multicenter Randomized Controlled Trial

Author(s) -

Joshua S. Davis,

Archana Sud,

Matthew O’Sullivan,

James O. Robinson,

Patricia Ferguson,

Hong Foo,

Sebastiaan J. van Hal,

Anna P. Ralph,

Benjamin P. Howden,

Paula Binks,

Adrienne Kirby,

Steven Y. C. Tong

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ808

Subject(s) - medicine , bacteremia , flucloxacillin , vancomycin , randomization , randomized controlled trial , surgery , staphylococcus aureus , antibiotics , microbiology and biotechnology , genetics , bacteria , biology

In vitro laboratory and animal studies demonstrate a synergistic role for the combination of vancomycin and antistaphylococcal β-lactams for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Prospective clinical data are lacking.

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