Prophylactic Antibiotics May Improve Outcome in Patients With Severe Burns Requiring Mechanical Ventilation: Propensity Score Analysis of a Japanese Nationwide Database | Zendy

Takashi Tagami | Zendy; Hiroki Matsui | Zendy; Kiyohide Fushimi | Zendy; Hideo Yasunaga | Zendy

Open Access

Prophylactic Antibiotics May Improve Outcome in Patients With Severe Burns Requiring Mechanical Ventilation: Propensity Score Analysis of a Japanese Nationwide Database

Author(s) -

Takashi Tagami,

Hiroki Matsui,

Kiyohide Fushimi,

Hideo Yasunaga

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ763

Subject(s) - medicine , propensity score matching , mechanical ventilation , confidence interval , antibiotics , surgery , biology , microbiology and biotechnology

The use of prophylactic antibiotics for severe burns in general settings remains controversial and is not suggested by recent guidelines owing to lack of evidence for efficacy. We examined the hypothesis that prophylactic systemic antibiotic therapy may reduce mortality in patients with severe burns.

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