Detection of Typhoidal and ParatyphoidalSalmonellain Blood by Real-time Polymerase Chain Reaction | Zendy

Sharon M. Tennant | Zendy; Deanna Toema | Zendy; Farah Naz Qamar | Zendy; Najeeha Talat Iqbal | Zendy; Mary Adetinuke Boyd | Zendy; Joanna M. Marshall | Zendy; William C. Blackwelder | Zendy; Yukun Wu | Zendy; Farheen Quadri | Zendy; Asia Khan | Zendy; Fátima Aziz | Zendy; Kumail Ahmad | Zendy; Adil Kalam | Zendy; Ehtisham Asif | Zendy; Shahida Qureshi | Zendy; Erum Khan | Zendy; Anita K. M. Zaidi | Zendy; Myron M. Levine | Zendy

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Detection of Typhoidal and ParatyphoidalSalmonellain Blood by Real-time Polymerase Chain Reaction

Author(s) -

Sharon M. Tennant,

Deanna Toema,

Farah Naz Qamar,

Najeeha Talat Iqbal,

Mary Adetinuke Boyd,

Joanna M. Marshall,

William C. Blackwelder,

Yukun Wu,

Farheen Quadri,

Asia Khan,

Fátima Aziz,

Kumail Ahmad,

Adil Kalam,

Ehtisham Asif,

Shahida Qureshi,

Erum Khan,

Anita K. M. Zaidi,

Myron M. Levine

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ726

Subject(s) - salmonella , typhoid fever , salmonella typhi , blood culture , medicine , polymerase chain reaction , microbiology and biotechnology , gold standard (test) , real time polymerase chain reaction , population , virology , bacteria , escherichia coli , biology , antibiotics , biochemistry , genetics , environmental health , gene

The gold standard for diagnosis of enteric fever caused by Salmonella Typhi or Salmonella Paratyphi A or B is bone marrow culture. However, because bone marrow aspiration is highly invasive, many hospitals and large health centers perform blood culture instead. As blood culture has several limitations, there is a need for novel typhoid diagnostics with improved sensitivity and more rapid time to detection.

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