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Evaluation of Cytokine Profile and HLA Association in Benznidazole Related Cutaneous Reactions in Patients With Chagas Disease
Author(s) -
Fernando Salvador,
Adrián SánchezMontalvá,
Mónica MartínezGallo,
Anna Sala,
Laura Viñas,
Marina García-Prat,
Gloria Aparicio,
Augusto Sao Avilés,
M A Artaza,
Berta Ferrer-Rosell,
Israel Molina
Publication year - 2015
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/civ690
Subject(s) - benznidazole , medicine , chagas disease , gastroenterology , adverse drug reaction , immunology , drug , pharmacology , trypanosoma cruzi , parasite hosting , world wide web , computer science
Benznidazole is the drug of choice for Chagas disease. The major drawback of this drug is the high adverse events rate, being cutaneous reactions the most frequent one, leading to definitive withdrawal of treatment in 15%-30% of patients.

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