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Lessons Learned From Enhancing Vaccine Pharmacovigilance Activities During PsA-TT Introduction in African Countries, 2010–2013
Author(s) -
Fabien Diomandé,
Tènè Marceline Yaméogo,
Kirsten Vannice,
MariePierre Préziosi,
Simonetta Viviani,
Claude-Roger Ouandaogo,
Modibo Keita,
Mamoudou Harouna Djingarey,
N Mbakuliyemo,
Bartholomew D. Akanmori,
Samba O. Sow,
Patrick Zuber
Publication year - 2015
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1093/cid/civ599
Subject(s) - medicine , pharmacovigilance , vaccination , meningococcal meningitis , mass vaccination , meningococcal vaccine , vaccine safety , family medicine , clinical trial , pediatrics , adverse effect , virology , immunology , immunization , neisseria meningitidis , antigen , biology , bacteria , genetics
The rollout of the group A meningococcal vaccine, PsA-TT, in Africa's meningitis belt countries represented the first introduction of a vaccine specifically designed for this part of the world. During the first year alone, the number of people who received the vaccine through mass vaccination campaigns was several hundredfold higher than that of subjects who participated in the closely monitored clinical trials. Implementation of a system to identify rare but potentially serious vaccine reactions was therefore a high priority in the design and implementation of those campaigns.

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