Ribavirin Reduces Absolute Lymphocyte Counts in Hepatitis C Virus–Infected Patients Treated With Interferon-Free, Direct-Acting Antiviral Regimens: Figure 1. | Zendy

Patrick R. Harrington | Zendy; Russell Fleischer | Zendy; Sarah Connelly | Zendy; Linda Lewis | Zendy; Jeffrey S. Murray | Zendy

Open Access

Ribavirin Reduces Absolute Lymphocyte Counts in Hepatitis C Virus–Infected Patients Treated With Interferon-Free, Direct-Acting Antiviral Regimens: Figure 1.

Author(s) -

Patrick R. Harrington,

Russell Fleischer,

Sarah Connelly,

Linda Lewis,

Jeffrey S. Murray

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ419

Subject(s) - medicine , ribavirin , virology , interferon , hepatitis c virus , immunology , alpha interferon , virus , lymphocyte , interferon alfa , hepacivirus , antiviral treatment , chronic hepatitis

In clinical trials of interferon-free, direct-acting antiviral treatment of chronic hepatitis C, subjects who received ribavirin had reduced lymphocyte levels (median decline of approximately 0.4-0.5 × 10(9) cells/L). A modest decline in CD4(+) T cells was observed in subjects with human immunodeficiency virus type 1 coinfection without documented opportunistic infections.

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