Deep Sequencing of HIV-1 in Cerebrospinal Fluid: Table 1. | Zendy

C. Y. William Tong | Zendy; Sinead Costelloe | Zendy; Jonathan Hubb | Zendy; Jane Mullen | Zendy; Siobhan O’Shea | Zendy; Mónica Marta | Zendy; Ranjababu Kulasegaram | Zendy; Simon Rackstraw | Zendy

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Deep Sequencing of HIV-1 in Cerebrospinal Fluid: Table 1.

Author(s) -

C. Y. William Tong,

Sinead Costelloe,

Jonathan Hubb,

Jane Mullen,

Siobhan O’Shea,

Mónica Marta,

Ranjababu Kulasegaram,

Simon Rackstraw

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ417

Subject(s) - cerebrospinal fluid , deep sequencing , medicine , viral load , virology , human immunodeficiency virus (hiv) , virus , dna sequencing , lentivirus , viral disease , rna , immunology , pathology , biology , genetics , gene , genome

Using deep sequencing, human immunodeficiency virus (HIV) resistance-associated mutations were detected as minority species in the cerebrospinal fluid (CSF) of 4 patients with higher HIV type 1 RNA load in CSF than in plasma, but not in 2 patients with higher plasma viral load. Deep sequencing could help our understanding of viral escape in the central nervous system.

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