The Addition of Intravenous Metronidazole to Oral Vancomycin is Associated With Improved Mortality in Critically Ill Patients WithClostridium difficileInfection | Zendy

Kristina Rokas | Zendy; James W. Johnson | Zendy; James Beardsley | Zendy; Christopher Ohl | Zendy; Vera Luther | Zendy; John Williamson | Zendy

Open Access

The Addition of Intravenous Metronidazole to Oral Vancomycin is Associated With Improved Mortality in Critically Ill Patients WithClostridium difficileInfection

Author(s) -

Kristina Rokas,

James W. Johnson,

James Beardsley,

Christopher Ohl,

Vera Luther,

John Williamson

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ409

Subject(s) - medicine , metronidazole , clostridium difficile , vancomycin , intensive care unit , surgery , intensive care medicine , antibiotics , genetics , bacteria , microbiology and biotechnology , biology , staphylococcus aureus

The optimal therapy for critically ill patients with Clostridium difficile infection (CDI) is not known. We aimed to evaluate mortality among critically ill patients with CDI who received oral vancomycin (monotherapy) vs oral vancomycin with intravenous (IV) metronidazole (combination therapy).

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