Improving Clinical Outcomes in Patients With Methicillin-SensitiveStaphylococcus aureusBacteremia and Reported Penicillin Allergy | Zendy

Kimberly G. Blumenthal | Zendy; Robert A. Parker | Zendy; Erica S. Shenoy | Zendy; Rochelle P. Walensky | Zendy

Open Access

Improving Clinical Outcomes in Patients With Methicillin-SensitiveStaphylococcus aureusBacteremia and Reported Penicillin Allergy

Author(s) -

Kimberly G. Blumenthal,

Robert A. Parker,

Erica S. Shenoy,

Rochelle P. Walensky

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ394

Subject(s) - medicine , bacteremia , staphylococcus aureus , penicillin , microbiology and biotechnology , penicillin allergy , allergy , staphylococcal infections , intensive care medicine , antibiotics , immunology , bacteria , genetics , biology

Methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia is a morbid infection. First-line MSSA therapies (nafcillin, oxacillin, cefazolin) are generally avoided in the 10% of patients reporting penicillin (PCN) allergy, but most of these patients are not truly allergic. We used a decision tree with sensitivity analyses to determine the optimal evaluation and treatment for patients with MSSA bacteremia and reported PCN allergy.

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