Impact of Sustained Eradication of NewPseudomonas aeruginosaInfection on Long-term Outcomes in Cystic Fibrosis | Zendy

Nicole Mayer-Hamblett | Zendy; Margaret Kloster | Zendy; Margaret Rosenfeld | Zendy; Ronald L. Gibson | Zendy; George RetschBogart | Zendy; Julia Emerson | Zendy; Valeria Thompson | Zendy; Bonnie W. Ramsey | Zendy

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Impact of Sustained Eradication of NewPseudomonas aeruginosaInfection on Long-term Outcomes in Cystic Fibrosis

Author(s) -

Nicole Mayer-Hamblett,

Margaret Kloster,

Margaret Rosenfeld,

Ronald L. Gibson,

George RetschBogart,

Julia Emerson,

Valeria Thompson,

Bonnie W. Ramsey

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ377

Subject(s) - medicine , hazard ratio , cystic fibrosis , pseudomonas aeruginosa , exacerbation , confidence interval , antibiotics , biology , bacteria , microbiology and biotechnology , genetics

Pseudomonas aeruginosa (Pa) is the most important pathogen infecting the airways in individuals with cystic fibrosis. A key question is whether children with newly acquired Pa infection who are able to achieve sustained eradication after early antipseudomonal therapy demonstrate improved long-term health outcomes compared with those who are unable to achieve a sustained microbiologic response.

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