Flu-like and Other Systemic Drug Reactions Among Persons Receiving Weekly Rifapentine Plus Isoniazid or Daily Isoniazid for Treatment of Latent Tuberculosis Infection in the PREVENT Tuberculosis Study | Zendy

Timothy R. Sterling | Zendy; Ruth N. Moro | Zendy; Andrey Borisov | Zendy; Elizabeth Phillips | Zendy; Gillian Shepherd | Zendy; N. F. Adkinson | Zendy; Stephen E. Weis | Zendy; Christine Ho | Zendy; Margarita E. Villarino | Zendy

Open Access

Flu-like and Other Systemic Drug Reactions Among Persons Receiving Weekly Rifapentine Plus Isoniazid or Daily Isoniazid for Treatment of Latent Tuberculosis Infection in the PREVENT Tuberculosis Study

Author(s) -

Timothy R. Sterling,

Ruth N. Moro,

Andrey Borisov,

Elizabeth Phillips,

Gillian Shepherd,

N. F. Adkinson,

Stephen E. Weis,

Christine Ho,

Margarita E. Villarino

Publication year - 2015

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1093/cid/civ323

Subject(s) - rifapentine , isoniazid , medicine , latent tuberculosis , tuberculosis , drug , pharmacology , mycobacterium tuberculosis , pathology

Weekly rifapentine plus isoniazid for 3 months (3HP) is as effective as daily isoniazid for 9 months (9H) for latent tuberculosis infection in high-risk persons, but there have been reports of possible flu-like syndrome.

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